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Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway

Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant.

Detalles Bibliográficos
Autores principales: Thomson, John P, Hunter, Jennifer M, Meehan, Richard R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054016/
https://www.ncbi.nlm.nih.gov/pubmed/23732041
http://dx.doi.org/10.1186/gb-2013-14-5-118
Descripción
Sumario:Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant.