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Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway

Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant.

Detalles Bibliográficos
Autores principales: Thomson, John P, Hunter, Jennifer M, Meehan, Richard R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054016/
https://www.ncbi.nlm.nih.gov/pubmed/23732041
http://dx.doi.org/10.1186/gb-2013-14-5-118
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author Thomson, John P
Hunter, Jennifer M
Meehan, Richard R
author_facet Thomson, John P
Hunter, Jennifer M
Meehan, Richard R
author_sort Thomson, John P
collection PubMed
description Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant.
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spelling pubmed-40540162014-06-13 Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway Thomson, John P Hunter, Jennifer M Meehan, Richard R Genome Biol Research Highlight Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant. BioMed Central 2013 2013-05-29 /pmc/articles/PMC4054016/ /pubmed/23732041 http://dx.doi.org/10.1186/gb-2013-14-5-118 Text en Copyright © 2013 BioMed Central Ltd
spellingShingle Research Highlight
Thomson, John P
Hunter, Jennifer M
Meehan, Richard R
Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title_full Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title_fullStr Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title_full_unstemmed Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title_short Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
title_sort deep c diving: mapping the low-abundance modifications of the dna demethylation pathway
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054016/
https://www.ncbi.nlm.nih.gov/pubmed/23732041
http://dx.doi.org/10.1186/gb-2013-14-5-118
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