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Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway
Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant.
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054016/ https://www.ncbi.nlm.nih.gov/pubmed/23732041 http://dx.doi.org/10.1186/gb-2013-14-5-118 |
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author | Thomson, John P Hunter, Jennifer M Meehan, Richard R |
author_facet | Thomson, John P Hunter, Jennifer M Meehan, Richard R |
author_sort | Thomson, John P |
collection | PubMed |
description | Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant. |
format | Online Article Text |
id | pubmed-4054016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40540162014-06-13 Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway Thomson, John P Hunter, Jennifer M Meehan, Richard R Genome Biol Research Highlight Two new studies imply that the reprogramming of 5-methylcytosine via TET- and TDG-family enzymes is both widespread throughout the genome and functionally significant. BioMed Central 2013 2013-05-29 /pmc/articles/PMC4054016/ /pubmed/23732041 http://dx.doi.org/10.1186/gb-2013-14-5-118 Text en Copyright © 2013 BioMed Central Ltd |
spellingShingle | Research Highlight Thomson, John P Hunter, Jennifer M Meehan, Richard R Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title | Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title_full | Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title_fullStr | Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title_full_unstemmed | Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title_short | Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway |
title_sort | deep c diving: mapping the low-abundance modifications of the dna demethylation pathway |
topic | Research Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054016/ https://www.ncbi.nlm.nih.gov/pubmed/23732041 http://dx.doi.org/10.1186/gb-2013-14-5-118 |
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