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Lsh regulates LTR retrotransposon repression independently of Dnmt3b function
BACKGROUND: DNA methylation contributes to genomic integrity by suppressing repeat-associated transposition. In addition to the canonical DNA methyltransferases, several auxiliary chromatin factors are required to maintain DNA methylation at intergenic and satellite repeats. The interaction between...
Autores principales: | Dunican, Donncha S, Cruickshanks, Hazel A, Suzuki, Masako, Semple, Colin A, Davey, Tracey, Arceci, Robert J, Greally, John, Adams, Ian R, Meehan, Richard R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054100/ https://www.ncbi.nlm.nih.gov/pubmed/24367978 http://dx.doi.org/10.1186/gb-2013-14-12-r146 |
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