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Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs

BACKGROUND: Mammalian transcriptomes contain thousands of long noncoding RNAs (lncRNAs). Some lncRNAs originate from intragenic enhancers which, when active, behave as alternative promoters producing transcripts that are processed using the canonical signals of their host gene. We have followed up t...

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Detalles Bibliográficos
Autores principales: Marques, Ana C, Hughes, Jim, Graham, Bryony, Kowalczyk, Monika S, Higgs, Doug R, Ponting, Chris P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054604/
https://www.ncbi.nlm.nih.gov/pubmed/24289259
http://dx.doi.org/10.1186/gb-2013-14-11-r131