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MOABS: model based analysis of bisulfite sequencing data
Bisulfite sequencing (BS-seq) is the gold standard for studying genome-wide DNA methylation. We developed MOABS to increase the speed, accuracy, statistical power and biological relevance of BS-seq data analysis. MOABS detects differential methylation with 10-fold coverage at single-CpG resolution b...
Autores principales: | Sun, Deqiang, Xi, Yuanxin, Rodriguez, Benjamin, Park, Hyun Jung, Tong, Pan, Meong, Mira, Goodell, Margaret A, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054608/ https://www.ncbi.nlm.nih.gov/pubmed/24565500 http://dx.doi.org/10.1186/gb-2014-15-2-r38 |
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