Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance

BACKGROUND: The extent to which development- and age-associated epigenetic changes are influenced by genetic, environmental and stochastic factors remains to be discovered. Twins provide an ideal model with which to investigate these influences but previous cross-sectional twin studies provide contr...

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Detalles Bibliográficos
Autores principales: Martino, David, Loke, Yuk Jin, Gordon, Lavinia, Ollikainen, Miina, Cruickshank, Mark N, Saffery, Richard, Craig, Jeffrey M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054827/
https://www.ncbi.nlm.nih.gov/pubmed/23697701
http://dx.doi.org/10.1186/gb-2013-14-5-r42

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