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Inferring gene function from evolutionary change in signatures of translation efficiency

BACKGROUND: The genetic code is redundant, meaning that most amino acids can be encoded by more than one codon. Highly expressed genes tend to use optimal codons to increase the accuracy and speed of translation. Thus, codon usage biases provide a signature of the relative expression levels of genes...

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Detalles Bibliográficos
Autores principales: Krisko, Anita, Copic, Tea, Gabaldón, Toni, Lehner, Ben, Supek, Fran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054840/
https://www.ncbi.nlm.nih.gov/pubmed/24580753
http://dx.doi.org/10.1186/gb-2014-15-3-r44

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