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Inferring gene function from evolutionary change in signatures of translation efficiency
BACKGROUND: The genetic code is redundant, meaning that most amino acids can be encoded by more than one codon. Highly expressed genes tend to use optimal codons to increase the accuracy and speed of translation. Thus, codon usage biases provide a signature of the relative expression levels of genes...
Autores principales: | Krisko, Anita, Copic, Tea, Gabaldón, Toni, Lehner, Ben, Supek, Fran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054840/ https://www.ncbi.nlm.nih.gov/pubmed/24580753 http://dx.doi.org/10.1186/gb-2014-15-3-r44 |
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