Methods for comprehensive experimental identification of RNA-protein interactions

The importance of RNA-protein interactions in controlling mRNA regulation and non-coding RNA function is increasingly appreciated. A variety of methods exist to comprehensively define RNA-protein interactions. We describe these methods and the considerations required for designing and interpreting t...

Descripción completa

Detalles Bibliográficos
Autores principales: McHugh, Colleen A, Russell, Pamela, Guttman, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054858/
https://www.ncbi.nlm.nih.gov/pubmed/24467948
http://dx.doi.org/10.1186/gb4152
_version_ 1782320556327043072
author McHugh, Colleen A
Russell, Pamela
Guttman, Mitchell
author_facet McHugh, Colleen A
Russell, Pamela
Guttman, Mitchell
author_sort McHugh, Colleen A
collection PubMed
description The importance of RNA-protein interactions in controlling mRNA regulation and non-coding RNA function is increasingly appreciated. A variety of methods exist to comprehensively define RNA-protein interactions. We describe these methods and the considerations required for designing and interpreting these experiments.
format Online
Article
Text
id pubmed-4054858
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-40548582015-01-27 Methods for comprehensive experimental identification of RNA-protein interactions McHugh, Colleen A Russell, Pamela Guttman, Mitchell Genome Biol Review The importance of RNA-protein interactions in controlling mRNA regulation and non-coding RNA function is increasingly appreciated. A variety of methods exist to comprehensively define RNA-protein interactions. We describe these methods and the considerations required for designing and interpreting these experiments. BioMed Central 2014 2014-01-27 /pmc/articles/PMC4054858/ /pubmed/24467948 http://dx.doi.org/10.1186/gb4152 Text en Copyright © 2014 McHugh et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
McHugh, Colleen A
Russell, Pamela
Guttman, Mitchell
Methods for comprehensive experimental identification of RNA-protein interactions
title Methods for comprehensive experimental identification of RNA-protein interactions
title_full Methods for comprehensive experimental identification of RNA-protein interactions
title_fullStr Methods for comprehensive experimental identification of RNA-protein interactions
title_full_unstemmed Methods for comprehensive experimental identification of RNA-protein interactions
title_short Methods for comprehensive experimental identification of RNA-protein interactions
title_sort methods for comprehensive experimental identification of rna-protein interactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054858/
https://www.ncbi.nlm.nih.gov/pubmed/24467948
http://dx.doi.org/10.1186/gb4152
work_keys_str_mv AT mchughcolleena methodsforcomprehensiveexperimentalidentificationofrnaproteininteractions
AT russellpamela methodsforcomprehensiveexperimentalidentificationofrnaproteininteractions
AT guttmanmitchell methodsforcomprehensiveexperimentalidentificationofrnaproteininteractions

Ejemplares similares