A Novel Potentiometric Sensor for Determination of Neurotoxin β-N-Oxalyl-L-α, β-Diaminopropionic Acid

A novel potentiometric sensor based on ionophore (Cd(NH(2)CH(2)CH(2)OCH(2)CH(2)OCH(2)CH(2)NH(2))Ag(3)(CN)(5)) for the determination of β-N-oxalyl-l-α, β-diaminopropionic acid (ODAP) is developed. The ODAP-selective membrane sensor demonstrates high sensitivity and short response time. The detection limit of the ODAP-selective membrane sensor is about 2 × 10(−6) mol L(-1) and the response time is shorter than 6 s. The linear dynamic range of the ODAP-selective membrane sensor is between ODAP concentrations of 1.0 × 10(−2) and 1 × 10(−6) mol L(-1). The ODAP-selective membrane sensor exhibits good operational stability for at least one week in dry conditions at 4–6°C. It has a reproducible and stable response during continuous work for at least 10 h with a relative standard deviation of 0.28% (n = 18).