Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions

A new study exploits the time-dependence of formaldehyde cross-linking in the commonly used chromatin immunoprecipitation (ChIP) assay to infer the on and off rates for site-specific chromatin interactions.

Detalles Bibliográficos
Autores principales: Keren, Leeat, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054896/
https://www.ncbi.nlm.nih.gov/pubmed/24257511
http://dx.doi.org/10.1186/gb4139
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author Keren, Leeat
Segal, Eran
author_facet Keren, Leeat
Segal, Eran
author_sort Keren, Leeat
collection PubMed
description A new study exploits the time-dependence of formaldehyde cross-linking in the commonly used chromatin immunoprecipitation (ChIP) assay to infer the on and off rates for site-specific chromatin interactions.
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spelling pubmed-40548962014-06-12 Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions Keren, Leeat Segal, Eran Genome Biol Research Highlight A new study exploits the time-dependence of formaldehyde cross-linking in the commonly used chromatin immunoprecipitation (ChIP) assay to infer the on and off rates for site-specific chromatin interactions. BioMed Central 2013 2013-11-21 /pmc/articles/PMC4054896/ /pubmed/24257511 http://dx.doi.org/10.1186/gb4139 Text en Copyright © 2013 BioMed Central Ltd.
spellingShingle Research Highlight
Keren, Leeat
Segal, Eran
Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title_full Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title_fullStr Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title_full_unstemmed Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title_short Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions
title_sort fixated on fixation: using chip to interrogate the dynamics of chromatin interactions
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054896/
https://www.ncbi.nlm.nih.gov/pubmed/24257511
http://dx.doi.org/10.1186/gb4139
work_keys_str_mv AT kerenleeat fixatedonfixationusingchiptointerrogatethedynamicsofchromatininteractions
AT segaleran fixatedonfixationusingchiptointerrogatethedynamicsofchromatininteractions

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