Prediction on the Inhibition Ratio of Pyrrolidine Derivatives on Matrix Metalloproteinase Based on Gene Expression Programming

Quantitative structure-activity relationships (QSAR) were developed to predict the inhibition ratio of pyrrolidine derivatives on matrix metalloproteinase via heuristic method (HM) and gene expression programming (GEP). The descriptors of 33 pyrrolidine derivatives were calculated by the software CO...

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Detalles Bibliográficos
Autores principales: Li, Yuqin, You, Guirong, Jia, Baoxiu, Si, Hongzong, Yao, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054925/
https://www.ncbi.nlm.nih.gov/pubmed/24971318
http://dx.doi.org/10.1155/2014/210672

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