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Large-scale generation of differentiated cells to achieve regenerative medicine
The effects of microgravity and fluid dynamic stress on embryoid bodies generated from pluripotent stem cells induce and direct their differentiation. Using this hydrodynamic effect combined with exogenous factors and three-dimensional culture, a new technique has been developed to produce functiona...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054968/ https://www.ncbi.nlm.nih.gov/pubmed/24444304 http://dx.doi.org/10.1186/scrt399 |
| _version_ | 1782320574695997440 |
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| author | Sasaki, Katsunori |
| author_facet | Sasaki, Katsunori |
| author_sort | Sasaki, Katsunori |
| collection | PubMed |
| description | The effects of microgravity and fluid dynamic stress on embryoid bodies generated from pluripotent stem cells induce and direct their differentiation. Using this hydrodynamic effect combined with exogenous factors and three-dimensional culture, a new technique has been developed to produce functional, effective, and safe hepatocytes for transplantation. The evolution of this technique will lead to automated production of a large number of differentiated cells and will significantly contribute to regenerative medicine. |
| format | Online Article Text |
| id | pubmed-4054968 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-40549682015-01-20 Large-scale generation of differentiated cells to achieve regenerative medicine Sasaki, Katsunori Stem Cell Res Ther Commentary The effects of microgravity and fluid dynamic stress on embryoid bodies generated from pluripotent stem cells induce and direct their differentiation. Using this hydrodynamic effect combined with exogenous factors and three-dimensional culture, a new technique has been developed to produce functional, effective, and safe hepatocytes for transplantation. The evolution of this technique will lead to automated production of a large number of differentiated cells and will significantly contribute to regenerative medicine. BioMed Central 2014-01-20 /pmc/articles/PMC4054968/ /pubmed/24444304 http://dx.doi.org/10.1186/scrt399 Text en Copyright © 2014 Sasaki; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Commentary Sasaki, Katsunori Large-scale generation of differentiated cells to achieve regenerative medicine |
| title | Large-scale generation of differentiated cells to achieve regenerative medicine |
| title_full | Large-scale generation of differentiated cells to achieve regenerative medicine |
| title_fullStr | Large-scale generation of differentiated cells to achieve regenerative medicine |
| title_full_unstemmed | Large-scale generation of differentiated cells to achieve regenerative medicine |
| title_short | Large-scale generation of differentiated cells to achieve regenerative medicine |
| title_sort | large-scale generation of differentiated cells to achieve regenerative medicine |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054968/ https://www.ncbi.nlm.nih.gov/pubmed/24444304 http://dx.doi.org/10.1186/scrt399 |
| work_keys_str_mv | AT sasakikatsunori largescalegenerationofdifferentiatedcellstoachieveregenerativemedicine |