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Modulation of β-amyloid by a single dose of GSK933776 in patients with mild Alzheimer’s disease: a phase I study

INTRODUCTION: In this study, we evaluated the safety and pharmacodynamic effects of the Fc-inactivated anti-β-amyloid (anti-Aβ) monoclonal antibody GSK933776 in patients with mild Alzheimer’s disease and mild cognitive impairment. Aβ and tau levels were investigated in cerebrospinal fluid (CSF), and...

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Detalles Bibliográficos
Autores principales:	Leyhe, Thomas, Andreasen, Niels, Simeoni, Monica, Reich, Arno, von Arnim, Christine AF, Tong, Xin, Yeo, Astrid, Khan, Shahid, Loercher, Amy, Chalker, Michelle, Hottenstein, Charles, Zetterberg, Henrik, Hilpert, Jan, Mistry, Prafull
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055052/ https://www.ncbi.nlm.nih.gov/pubmed/24716469 http://dx.doi.org/10.1186/alzrt249

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