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The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4

G protein–coupled receptor (GPCR) sorting into the degradative pathway is important for limiting the duration and magnitude of signaling. Agonist activation of the GPCR CXCR4 induces its rapid ubiquitination and sorting to lysosomes via the endosomal sorting complex required for transport (ESCRT) pa...

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Detalles Bibliográficos
Autores principales: Holleman, Justine, Marchese, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055268/
https://www.ncbi.nlm.nih.gov/pubmed/24790097
http://dx.doi.org/10.1091/mbc.E13-10-0612

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