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A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission

The GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial division, but the mechanisms remain poorly understood. Much of what is attributed to Drp1’s mechanism of action in mitochondrial membrane fission parallels that of prototypical dynamin in endocytic vesicle scission. Unlike the case...

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Detalles Bibliográficos
Autores principales: Macdonald, Patrick J., Stepanyants, Natalia, Mehrotra, Niharika, Mears, Jason A., Qi, Xin, Sesaki, Hiromi, Ramachandran, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055269/
https://www.ncbi.nlm.nih.gov/pubmed/24790094
http://dx.doi.org/10.1091/mbc.E14-02-0728

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