IL-6 Impairs Myogenic Differentiation by Downmodulation of p90RSK/eEF2 and mTOR/p70S6K Axes, without Affecting AKT Activity

IL-6 is a multifaceted pleiotropic cytokine, which is produced by a variety of cell types and targets different cells and tissues. In physiological conditions, IL-6 can be locally and transiently produced by skeletal muscle and plays an important role in muscle homeostasis. Circulating IL-6 levels a...

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Detalles Bibliográficos
Autores principales: Pelosi, Michele, De Rossi, Manuela, Barberi, Laura, Musarò, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055274/
https://www.ncbi.nlm.nih.gov/pubmed/24967341
http://dx.doi.org/10.1155/2014/206026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055274/
https://www.ncbi.nlm.nih.gov/pubmed/24967341
http://dx.doi.org/10.1155/2014/206026

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