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The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells

The inhibition of the mammalian target of rapamycin (mTOR) signaling pathway promotes the initiation of autophagy, and the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated protein kinase (ERK) is well known to induce autophagy. Autophagy is a self-defense mechanism of cancer ce...

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Detalles Bibliográficos
Autores principales: NAKAMURA, OSAMU, HITORA, TOSHIAKI, YAMAGAMI, YOSHIKI, MORI, MASAKI, NISHIMURA, HIDEKI, HORIE, RYOSUKE, YAMAGUCHI, KONOSUKE, YAMAMOTO, TETSUJI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055350/
https://www.ncbi.nlm.nih.gov/pubmed/24676456
http://dx.doi.org/10.3892/ijmm.2014.1715