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Protein Conservation and Variation Suggest Mechanisms of Cell Type-Specific Modulation of Signaling Pathways
Many proteins and signaling pathways are present in most cell types and tissues and yet perform specialized functions. To elucidate mechanisms by which these ubiquitous pathways are modulated, we overlaid information about cross-cell line protein abundance and variability, and evolutionary conservat...
Autores principales: | Schaefer, Martin H., Yang, Jae-Seong, Serrano, Luis, Kiel, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055412/ https://www.ncbi.nlm.nih.gov/pubmed/24922536 http://dx.doi.org/10.1371/journal.pcbi.1003659 |
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