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Enhanced efficacy of combination therapy with adeno-associated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma
Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis, and the antitumor effect of adeno-associated virus (AAV)-mediated PEDF expression has been demonstrated in a range of animal models. The combined treatment of low-dose chemotherapy and gene therapy inhibits the growth of...
Autores principales: | HE, SHA-SHA, WU, QIN-JIE, GONG, CHANG YANG, LUO, SHUN-TAO, ZHANG, SHUANG, LI, MENG, LU, LIAN, WEI, YU-QUAN, YANG, LI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055432/ https://www.ncbi.nlm.nih.gov/pubmed/24714917 http://dx.doi.org/10.3892/mmr.2014.2117 |
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