Depression in Primary Care Patients with Coronary Heart Disease: Baseline Findings from the UPBEAT UK Study

BACKGROUND: An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline. METHOD: Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems. RESULTS: 803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11–13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93–7.14), experiencing chest pain (OR 3.27, 95% CI 1.58–6.76), other pains or discomfort (OR 3.39, 95% CI 1.42–8.10), younger age (OR 0.95 per year 95% CI 0.92–0.98). CONCLUSION: Problems living alone, chest pain and disability are important predictors of depression in this population.