Rift Valley Fever Virus Encephalitis Is Associated with an Ineffective Systemic Immune Response and Activated T Cell Infiltration into the CNS in an Immunocompetent Mouse Model

BACKGROUND: Rift Valley fever virus (RVFV) causes outbreaks of severe disease in livestock and humans throughout Africa and the Arabian Peninsula. In people, RVFV generally causes a self-limiting febrile illness but in a subset of individuals, it progresses to more serious disease. One manifestation...

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Detalles Bibliográficos
Autores principales: Dodd, Kimberly A., McElroy, Anita K., Jones, Tara L., Zaki, Sherif R., Nichol, Stuart T., Spiropoulou, Christina F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055548/
https://www.ncbi.nlm.nih.gov/pubmed/24922480
http://dx.doi.org/10.1371/journal.pntd.0002874

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