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Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions
AMP-activated protein kinase (AMPK) is an evolutionarily conserved master regulator of metabolism and a therapeutic target in type 2 diabetes. As an energy sensor, AMPK activity is responsive to both metabolic inputs, for instance the ratio of AMP to ATP, and numerous hormonal cues. As in mammals, e...
Autores principales: | Cunningham, Katherine A., Bouagnon, Aude D., Barros, Alexandre G., Lin, Lin, Malard, Leandro, Romano-Silva, Marco Aurélio, Ashrafi, Kaveh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055570/ https://www.ncbi.nlm.nih.gov/pubmed/24921650 http://dx.doi.org/10.1371/journal.pgen.1004394 |
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