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Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein

BACKGROUND: Phytochemical-mediated alterations in P-glycoprotein (P-gp) activity may result in herb-drug interactions by altering drug pharmacokinetics. Shengmai-san, a traditional Chinese herbal medicine composed by Panax Ginseng, Ophiopogon Japonicus, and Schisandra Chinensis, is routinely being u...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Zhou, Yuanyuan, Zhang, Jingwei, Rao, Tai, Zhou, Lijun, Xing, Rong, Wang, Qian, Fu, Hanxu, Hao, Kun, Xie, Lin, Wang, Guangji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055595/
https://www.ncbi.nlm.nih.gov/pubmed/24922060
http://dx.doi.org/10.1371/journal.pone.0098717