Podocytes Degrade Endocytosed Albumin Primarily in Lysosomes

Albuminuria is a strong, independent predictor of chronic kidney disease progression. We hypothesize that podocyte processing of albumin via the lysosome may be an important determinant of podocyte injury and loss. A human urine derived podocyte-like epithelial cell (HUPEC) line was used for in vitr...

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Detalles Bibliográficos
Autores principales: Carson, John M., Okamura, Kayo, Wakashin, Hidefumi, McFann, Kim, Dobrinskikh, Evgenia, Kopp, Jeffrey B., Blaine, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055698/
https://www.ncbi.nlm.nih.gov/pubmed/24924335
http://dx.doi.org/10.1371/journal.pone.0099771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055698/
https://www.ncbi.nlm.nih.gov/pubmed/24924335
http://dx.doi.org/10.1371/journal.pone.0099771

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