Cargando…

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models

The aim of this study is to determine if ultraviolet light (UVC) irradiation in combination with fluorescence-guided surgery (FGS) can eradicate metastatic human pancreatic cancer in orthotopic nude–mouse models. Two weeks after orthotopic implantation of human MiaPaCa-2 pancreatic cancer cells, exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hiroshima, Yukihiko, Maawy, Ali, Zhang, Yong, Sato, Sho, Murakami, Takashi, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Bouvet, Michael, Endo, Itaru, Hoffman, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055701/ https://www.ncbi.nlm.nih.gov/pubmed/24924955 http://dx.doi.org/10.1371/journal.pone.0099977

Ejemplares similares

Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

The Tumor-Educated-Macrophage Increase of Malignancy of Human Pancreatic Cancer Is Prevented by Zoledronic Acid
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy
por: Hiroshima, Yukihiko, et al.
Publicado: (2016)

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models
por: Murakami, Takashi, et al.
Publicado: (2015)

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models
por: Murakami, Takashi, et al.
Publicado: (2015)

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model
por: Murakami, Takashi, et al.
Publicado: (2015)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Fluorescence-Guided Surgery of Retroperitoneal-Implanted Human Fibrosarcoma in Nude Mice Delays or Eliminates Tumor Recurrence and Increases Survival Compared to Bright-Light Surgery
por: Uehara, Fuminari, et al.
Publicado: (2015)

Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model
por: Yano, Shuya, et al.
Publicado: (2016)

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model
por: Murakami, Takashi, et al.
Publicado: (2016)

MUC1 Selectively Targets Human Pancreatic Cancer in Orthotopic Nude Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2015)

Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery
por: Yano, Shuya, et al.
Publicado: (2015)

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma
por: Yano, Shuya, et al.
Publicado: (2015)

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice
por: Matsumoto, Yasunori, et al.
Publicado: (2015)

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice
por: Miwa, Shinji, et al.
Publicado: (2014)

Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models
por: Murakami, Takashi, et al.
Publicado: (2019)

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R
por: Miwa, Shinji, et al.
Publicado: (2014)

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2017)

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy
por: Miyake, Kentaro, et al.
Publicado: (2017)

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2016)

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy
por: Miyake, Kentaro, et al.
Publicado: (2018)

Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer
por: Maawy, Ali A., et al.
Publicado: (2015)

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model
por: Yamamoto, Mako, et al.
Publicado: (2016)

Role of the tumor microenvironment in pancreatic cancer
por: Murakami, Takashi, et al.
Publicado: (2019)

Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture
por: Mii, Sumiyuki, et al.
Publicado: (2013)

Polyethylene Glycol (PEG) Linked to Near Infrared (NIR) Dyes Conjugated to Chimeric Anti-Carcinoembryonic Antigen (CEA) Antibody Enhances Imaging of Liver Metastases in a Nude-Mouse Model of Human Colon Cancer
por: Maawy, Ali A., et al.
Publicado: (2014)

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations
por: Miyake, Kentaro, et al.
Publicado: (2018)

High-efficacy targeting of colon-cancer liver metastasis with Salmonella typhimurium A1-R via intra-portal-vein injection in orthotopic nude-mouse models
por: Kawaguchi, Kei, et al.
Publicado: (2016)

Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug
por: Murakami, Takashi, et al.
Publicado: (2016)

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2015)

Fluorescent-Antibody Targeting of Insulin-Like Growth Factor-1 Receptor Visualizes Metastatic Human Colon Cancer in Orthotopic Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2016)

Tumor-targeting adenovirus OBP-401 inhibits primary and metastatic tumor growth of triple-negative breast cancer in orthotopic nude-mouse models
por: Yano, Shuya, et al.
Publicado: (2016)

A giant adrenal pseudocyst presenting with right hypochondralgia and fever: a case report
por: Momiyama, Masashi, et al.
Publicado: (2011)

Splenectomy is associated with an aggressive tumor growth pattern and altered host immunity in an orthotopic syngeneic murine pancreatic cancer model
por: Hwang, Ho Kyoung, et al.
Publicado: (2017)

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application
por: Higuchi, Takashi, et al.
Publicado: (2022)

UVC disinfection robot
por: Guettari, Moez, et al.
Publicado: (2020)

Effect of UVC Irradiation on the Oxidation of Histidine in Monoclonal Antibodies
por: Miyahara, Yuya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_polas7olstche0prp4n9qdap1l