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Biosynthesis and deficiencies of glycosylphosphatidylinositol

At least 150 different human proteins are anchored to the outer leaflet of the plasma membrane via glycosylphosphatidylinositol (GPI). GPI preassembled in the endoplasmic reticulum is attached to the protein’s carboxyl-terminus as a post-translational modification by GPI transamidase. Twenty-two PIG...

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Detalles Bibliográficos
Autor principal: KINOSHITA, Taroh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055706/
https://www.ncbi.nlm.nih.gov/pubmed/24727937
http://dx.doi.org/10.2183/pjab.90.130