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Functional Characterization of a Novel Family of Acetylcholine-Gated Chloride Channels in Schistosoma mansoni

Acetylcholine is the canonical excitatory neurotransmitter of the mammalian neuromuscular system. However, in the trematode parasite Schistosoma mansoni, cholinergic stimulation leads to muscle relaxation and a flaccid paralysis, suggesting an inhibitory mode of action. Information about the pharmac...

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Detalles Bibliográficos
Autores principales:	MacDonald, Kevin, Buxton, Samuel, Kimber, Michael J., Day, Tim A., Robertson, Alan P., Ribeiro, Paula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055736/ https://www.ncbi.nlm.nih.gov/pubmed/24945827 http://dx.doi.org/10.1371/journal.ppat.1004181

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