The Triggering Receptor Expressed on Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms and Exerts Detrimental Effects during Pneumococcal Pneumonia

Phagocytosis and inflammation within the lungs is crucial for host defense during bacterial pneumonia. Triggering receptor expressed on myeloid cells (TREM)-2 was proposed to negatively regulate TLR-mediated responses and enhance phagocytosis by macrophages, but the role of TREM-2 in respiratory tra...

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Detalles Bibliográficos
Autores principales: Sharif, Omar, Gawish, Riem, Warszawska, Joanna M., Martins, Rui, Lakovits, Karin, Hladik, Anastasiya, Doninger, Bianca, Brunner, Julia, Korosec, Ana, Schwarzenbacher, Roland E., Berg, Tiina, Kralovics, Robert, Colinge, Jacques, Mesteri, Ildiko, Gilfillan, Susan, Salmaggi, Andrea, Verschoor, Admar, Colonna, Marco, Knapp, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055749/
https://www.ncbi.nlm.nih.gov/pubmed/24945405
http://dx.doi.org/10.1371/journal.ppat.1004167

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