Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance

Bacterial signaling systems are prime drug targets for combating the global health threat of antibiotic resistant bacterial infections including those caused by Staphylococcus aureus. S. aureus is the primary cause of acute bacterial skin and soft tissue infections (SSTIs) and the quorum sensing ope...

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Detalles Bibliográficos
Autores principales: Sully, Erin K., Malachowa, Natalia, Elmore, Bradley O., Alexander, Susan M., Femling, Jon K., Gray, Brian M., DeLeo, Frank R., Otto, Michael, Cheung, Ambrose L., Edwards, Bruce S., Sklar, Larry A., Horswill, Alexander R., Hall, Pamela R., Gresham, Hattie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055767/
https://www.ncbi.nlm.nih.gov/pubmed/24945495
http://dx.doi.org/10.1371/journal.ppat.1004174

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