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The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis
The aim of the present study was to identify the influence of vertebral fracture (VF) on the functional disability in patients with rheumatoid arthritis (RA). This study consecutively enrolled 100 female patients aged 50 yr or older with RA. All participants underwent lateral imaging of the thoracol...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055822/ https://www.ncbi.nlm.nih.gov/pubmed/24932090 http://dx.doi.org/10.3346/jkms.2014.29.6.859 |
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author | Cho, Soo-Kyung Lee, Joo-Hyun Han, Minkyung Lee, Seunghun Kim, Ji Young Ryu, Jeong Ah Choi, Yun Young Bae, Sang-Cheol Sung, Yoon-Kyoung |
author_facet | Cho, Soo-Kyung Lee, Joo-Hyun Han, Minkyung Lee, Seunghun Kim, Ji Young Ryu, Jeong Ah Choi, Yun Young Bae, Sang-Cheol Sung, Yoon-Kyoung |
author_sort | Cho, Soo-Kyung |
collection | PubMed |
description | The aim of the present study was to identify the influence of vertebral fracture (VF) on the functional disability in patients with rheumatoid arthritis (RA). This study consecutively enrolled 100 female patients aged 50 yr or older with RA. All participants underwent lateral imaging of the thoracolumbar spine by simple radiography to identify any VFs. They also completed questionnaires via interview regarding demographics, medical history, and disease outcomes including functional disability. We used univariate analysis to evaluate associations between functional disability and VF, and made multivariate logistic regression models to test independent effect of the presence of VF, the number of VFs, and the severity of VF on functional disability. Among the 100 RA patients, 47 had at least one VF, but 34 of them were asymptomatic that they had experienced a fracture. The multiple VFs ≥ 3 (OR, 8.95; 95% CI, 1.77-44.15, P = 0.01) and moderate or severe VF (OR, 3.38; 95% CI, 1.26-9.04, P = 0.02) were related to disability in univariate analysis. The multiple VFs ≥ 3 (OR, 6.13; 95% CI, 1.02-36.94, P = 0.048) was associated with functional disability of RA patients after adjusting various confounders and it was mainly in walking and arising. The VF might be an important factor which affects functional disability in RA patients. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-4055822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-40558222014-06-15 The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis Cho, Soo-Kyung Lee, Joo-Hyun Han, Minkyung Lee, Seunghun Kim, Ji Young Ryu, Jeong Ah Choi, Yun Young Bae, Sang-Cheol Sung, Yoon-Kyoung J Korean Med Sci Original Article The aim of the present study was to identify the influence of vertebral fracture (VF) on the functional disability in patients with rheumatoid arthritis (RA). This study consecutively enrolled 100 female patients aged 50 yr or older with RA. All participants underwent lateral imaging of the thoracolumbar spine by simple radiography to identify any VFs. They also completed questionnaires via interview regarding demographics, medical history, and disease outcomes including functional disability. We used univariate analysis to evaluate associations between functional disability and VF, and made multivariate logistic regression models to test independent effect of the presence of VF, the number of VFs, and the severity of VF on functional disability. Among the 100 RA patients, 47 had at least one VF, but 34 of them were asymptomatic that they had experienced a fracture. The multiple VFs ≥ 3 (OR, 8.95; 95% CI, 1.77-44.15, P = 0.01) and moderate or severe VF (OR, 3.38; 95% CI, 1.26-9.04, P = 0.02) were related to disability in univariate analysis. The multiple VFs ≥ 3 (OR, 6.13; 95% CI, 1.02-36.94, P = 0.048) was associated with functional disability of RA patients after adjusting various confounders and it was mainly in walking and arising. The VF might be an important factor which affects functional disability in RA patients. GRAPHICAL ABSTRACT: [Image: see text] The Korean Academy of Medical Sciences 2014-06 2014-05-30 /pmc/articles/PMC4055822/ /pubmed/24932090 http://dx.doi.org/10.3346/jkms.2014.29.6.859 Text en © 2014 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Cho, Soo-Kyung Lee, Joo-Hyun Han, Minkyung Lee, Seunghun Kim, Ji Young Ryu, Jeong Ah Choi, Yun Young Bae, Sang-Cheol Sung, Yoon-Kyoung The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title | The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title_full | The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title_fullStr | The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title_full_unstemmed | The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title_short | The Influence of Vertebral Fracture on the Functional Disability of Patients with Rheumatoid Arthritis |
title_sort | influence of vertebral fracture on the functional disability of patients with rheumatoid arthritis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055822/ https://www.ncbi.nlm.nih.gov/pubmed/24932090 http://dx.doi.org/10.3346/jkms.2014.29.6.859 |
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