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Reduction in parvalbumin-positive interneurons and inhibitory input in the cortex of mice with experimental autoimmune encephalomyelitis

In multiple sclerosis (MS), inflammation leads to damage of central nervous system myelin and axons. Previous studies have postulated impaired GABA transmission in MS, and recent postmortem analysis has shown that GABAergic parvalbumin (PV)-positive interneurons are decreased in the primary motor co...

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Detalles Bibliográficos
Autores principales: Falco, Anna, Pennucci, Roberta, Brambilla, Elena, de Curtis, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055863/
https://www.ncbi.nlm.nih.gov/pubmed/24770856
http://dx.doi.org/10.1007/s00221-014-3944-7

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