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Clinical and non-targeted metabolomic profiling of homozygous carriers of Transcription Factor 7-like 2 variant rs7903146

An important role of the type 2 diabetes risk variant rs7903146 in TCF7L2 in metabolic actions of various tissues, in particular of the liver, has recently been demonstrated by functional animal studies. Accordingly, the TT diabetes risk allele may lead to currently unknown alterations in human. Our...

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Detalles Bibliográficos
Autores principales:	Wagner, Robert, Li, Jia, Kenar, Erhan, Kohlbacher, Oliver, Machicao, Fausto, Häring, Hans-Ulrich, Fritsche, Andreas, Xu, Guowang, Lehmann, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055885/ https://www.ncbi.nlm.nih.gov/pubmed/24925104 http://dx.doi.org/10.1038/srep05296

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