Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin

INTRODUCTION: Ventilator-induced lung injury (VILI) contributes to morbidity and mortality in acute respiratory distress syndrome (ARDS). Particularly pre-injured lungs are susceptible to VILI despite protective ventilation. In a previous study, the endogenous peptide adrenomedullin (AM) protected m...

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Detalles Bibliográficos
Autores principales: Müller-Redetzky, Holger C, Will, Daniel, Hellwig, Katharina, Kummer, Wolfgang, Tschernig, Thomas, Pfeil, Uwe, Paddenberg, Renate, Menger, Michael D, Kershaw, Olivia, Gruber, Achim D, Weissmann, Norbert, Hippenstiel, Stefan, Suttorp, Norbert, Witzenrath, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056010/
https://www.ncbi.nlm.nih.gov/pubmed/24731244
http://dx.doi.org/10.1186/cc13830

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