Direct T cell–tumour interaction triggers T(H)1 phenotype activation through the modification of the mesenchymal stromal cells transcriptional programme

BACKGROUND: Mesenchymal stromal cells (MSCs) are heterogeneous cells with immunoregulatory and wound-healing properties. In cancer, they are known to be an essential part of the tumour microenvironment. However, their role in tumour growth and rejection remains unclear. To investigate this, we co-cu...

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Detalles Bibliográficos
Autores principales: Jin, P, Civini, S, Zhao, Y, De Giorgi, V, Ren, J, Sabatino, M, Jin, J, Wang, H, Bedognetti, D, Marincola, F, Stroncek, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056054/
https://www.ncbi.nlm.nih.gov/pubmed/24809778
http://dx.doi.org/10.1038/bjc.2014.235

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