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Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery

INTRODUCTION: Neutrophil recovery has been implicated in deterioration of oxygenation and exacerbation of preexisting acute lung injury (ALI). The aim of this study was to investigate whether imatinib or nilotinib was effective on lipopolysaccharide (LPS)-induced ALI during neutropenia recovery in m...

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Detalles Bibliográficos
Autores principales: Kim, In Kyoung, Rhee, Chin Kook, Yeo, Chang Dong, Kang, Hyeon Hui, Lee, Dong Gun, Lee, Sang Haak, Kim, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056323/
https://www.ncbi.nlm.nih.gov/pubmed/23787115
http://dx.doi.org/10.1186/cc12786

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