DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer

Simultaneous interrogation of tumor genomes and transcriptomes is underway in unprecedented global efforts. Yet, despite the essential need to separate driver mutations modulating gene expression networks from transcriptionally inert passenger mutations, robust computational methods to ascertain the...

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Detalles Bibliográficos
Autores principales: Bashashati, Ali, Haffari, Gholamreza, Ding, Jiarui, Ha, Gavin, Lui, Kenneth, Rosner, Jamie, Huntsman, David G, Caldas, Carlos, Aparicio, Samuel A, Shah, Sohrab P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056374/
https://www.ncbi.nlm.nih.gov/pubmed/23383675
http://dx.doi.org/10.1186/gb-2012-13-12-r124

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