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Hyperglycemia-induced diaphragm weakness is mediated by oxidative stress

INTRODUCTION: A major consequence of ICU-acquired weakness (ICUAW) is diaphragm weakness, which prolongs the duration of mechanical ventilation. Hyperglycemia (HG) is a risk factor for ICUAW. However, the mechanisms underlying HG-induced respiratory muscle weakness are not known. Excessive reactive...

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Detalles Bibliográficos
Autores principales: Callahan, Leigh A, Supinski, Gerald S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056378/
https://www.ncbi.nlm.nih.gov/pubmed/24886999
http://dx.doi.org/10.1186/cc13855