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Fever in sepsis: is it cool to be hot?

Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality. Combined with recent data suggesting that feb...

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Detalles Bibliográficos
Autores principales: Young, Paul J, Bellomo, Rinaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056432/
https://www.ncbi.nlm.nih.gov/pubmed/24521542
http://dx.doi.org/10.1186/cc13726
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author Young, Paul J
Bellomo, Rinaldo
author_facet Young, Paul J
Bellomo, Rinaldo
author_sort Young, Paul J
collection PubMed
description Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality. Combined with recent data suggesting that febrile patients with infections have the lowest mortality risk, the study raises the question of whether inducing therapeutic hyperthermia might be beneficial in this patient group. Body temperature is easily measured and manipulated in the ICU, and interventional trials defining the most appropriate temperature targets in ICU patients with infections are urgently needed. One such study is in progress.
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spelling pubmed-40564322015-02-13 Fever in sepsis: is it cool to be hot? Young, Paul J Bellomo, Rinaldo Crit Care Commentary Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality. Combined with recent data suggesting that febrile patients with infections have the lowest mortality risk, the study raises the question of whether inducing therapeutic hyperthermia might be beneficial in this patient group. Body temperature is easily measured and manipulated in the ICU, and interventional trials defining the most appropriate temperature targets in ICU patients with infections are urgently needed. One such study is in progress. BioMed Central 2014 2014-02-13 /pmc/articles/PMC4056432/ /pubmed/24521542 http://dx.doi.org/10.1186/cc13726 Text en Copyright © 2014 BioMed Central Ltd.
spellingShingle Commentary
Young, Paul J
Bellomo, Rinaldo
Fever in sepsis: is it cool to be hot?
title Fever in sepsis: is it cool to be hot?
title_full Fever in sepsis: is it cool to be hot?
title_fullStr Fever in sepsis: is it cool to be hot?
title_full_unstemmed Fever in sepsis: is it cool to be hot?
title_short Fever in sepsis: is it cool to be hot?
title_sort fever in sepsis: is it cool to be hot?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056432/
https://www.ncbi.nlm.nih.gov/pubmed/24521542
http://dx.doi.org/10.1186/cc13726
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