Isotype Switching Increases Efficacy of Antibody Protection against Staphylococcal Enterotoxin B-Induced Lethal Shock and Staphylococcus aureus Sepsis in Mice

Staphylococcal enterotoxin B (SEB) is a potent toxin that is produced by Staphylococcus aureus strains and is classified as a category B select agent. We have previously shown that monoclonal antibody (MAb) 20B1, a murine anti-SEB IgG1, successfully treats SEB-induced lethal shock (SEBILS) and bacte...

Descripción completa

Detalles Bibliográficos
Autores principales: Varshney, Avanish K., Wang, Xiaobo, Aguilar, Jorge L., Scharff, Matthew D., Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056548/
https://www.ncbi.nlm.nih.gov/pubmed/24917594
http://dx.doi.org/10.1128/mBio.01007-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056548/
https://www.ncbi.nlm.nih.gov/pubmed/24917594
http://dx.doi.org/10.1128/mBio.01007-14

Ejemplares similares