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Measuring glomerular filtration rate in the intensive care unit: no substitutes please
Acute kidney injury (AKI), due to its increasing incidence, associated morbidity and mortality, and potential for development of chronic kidney disease with acceleration to end-stage renal disease, has become of major interest to nephrologists and critical care physicians. The development of biomark...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056753/ https://www.ncbi.nlm.nih.gov/pubmed/24004539 http://dx.doi.org/10.1186/cc12876 |
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author | Molitoris, Bruce A |
author_facet | Molitoris, Bruce A |
author_sort | Molitoris, Bruce A |
collection | PubMed |
description | Acute kidney injury (AKI), due to its increasing incidence, associated morbidity and mortality, and potential for development of chronic kidney disease with acceleration to end-stage renal disease, has become of major interest to nephrologists and critical care physicians. The development of biomarkers to diagnose AKI, quantify risk and predict prognosis is receiving considerable attention. Yet techniques to accurately assess functional changes within patients still rely on the use of an insensitive marker (creatinine), creatinine-based estimating equations and unreliable urinary tests. Therefore, it is critical that functional tests be developed and used in combination with biomarkers, thus allowing improved care in AKI and chronic kidney disease patient populations. |
format | Online Article Text |
id | pubmed-4056753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40567532014-06-14 Measuring glomerular filtration rate in the intensive care unit: no substitutes please Molitoris, Bruce A Crit Care Commentary Acute kidney injury (AKI), due to its increasing incidence, associated morbidity and mortality, and potential for development of chronic kidney disease with acceleration to end-stage renal disease, has become of major interest to nephrologists and critical care physicians. The development of biomarkers to diagnose AKI, quantify risk and predict prognosis is receiving considerable attention. Yet techniques to accurately assess functional changes within patients still rely on the use of an insensitive marker (creatinine), creatinine-based estimating equations and unreliable urinary tests. Therefore, it is critical that functional tests be developed and used in combination with biomarkers, thus allowing improved care in AKI and chronic kidney disease patient populations. BioMed Central 2013 2013-09-04 /pmc/articles/PMC4056753/ /pubmed/24004539 http://dx.doi.org/10.1186/cc12876 Text en Copyright © 2013 BioMed Central Ltd. |
spellingShingle | Commentary Molitoris, Bruce A Measuring glomerular filtration rate in the intensive care unit: no substitutes please |
title | Measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
title_full | Measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
title_fullStr | Measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
title_full_unstemmed | Measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
title_short | Measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
title_sort | measuring glomerular filtration rate in the intensive care unit: no substitutes
please |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056753/ https://www.ncbi.nlm.nih.gov/pubmed/24004539 http://dx.doi.org/10.1186/cc12876 |
work_keys_str_mv | AT molitorisbrucea measuringglomerularfiltrationrateintheintensivecareunitnosubstitutesplease |