Detrimental role of humoral signalling in cardio-renal cross-talk

In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzì and colleagues discuss the relevance of humoral signalling between heart and kidney, focus...

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Autores principales: Cantaluppi, Vincenzo, Dellepiane, Sergio, Quercia, Alessandro D, Ferrario, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056806/
https://www.ncbi.nlm.nih.gov/pubmed/24451176
http://dx.doi.org/10.1186/cc13704
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author Cantaluppi, Vincenzo
Dellepiane, Sergio
Quercia, Alessandro D
Ferrario, Silvia
author_facet Cantaluppi, Vincenzo
Dellepiane, Sergio
Quercia, Alessandro D
Ferrario, Silvia
author_sort Cantaluppi, Vincenzo
collection PubMed
description In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzì and colleagues discuss the relevance of humoral signalling between heart and kidney, focusing on type 1 and type 3 cardio-renal syndrome. We herein review the mechanisms of heart-kidney cross-talk, discussing the role of circulating detrimental mediators in the pathogenetic mechanisms of cardio-renal syndrome.
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spelling pubmed-40568062015-01-22 Detrimental role of humoral signalling in cardio-renal cross-talk Cantaluppi, Vincenzo Dellepiane, Sergio Quercia, Alessandro D Ferrario, Silvia Crit Care Commentary In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzì and colleagues discuss the relevance of humoral signalling between heart and kidney, focusing on type 1 and type 3 cardio-renal syndrome. We herein review the mechanisms of heart-kidney cross-talk, discussing the role of circulating detrimental mediators in the pathogenetic mechanisms of cardio-renal syndrome. BioMed Central 2014 2014-01-22 /pmc/articles/PMC4056806/ /pubmed/24451176 http://dx.doi.org/10.1186/cc13704 Text en Copyright © 2014 BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 The licensee has exclusive rights to distribute this article, in any medium, for 12 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Cantaluppi, Vincenzo
Dellepiane, Sergio
Quercia, Alessandro D
Ferrario, Silvia
Detrimental role of humoral signalling in cardio-renal cross-talk
title Detrimental role of humoral signalling in cardio-renal cross-talk
title_full Detrimental role of humoral signalling in cardio-renal cross-talk
title_fullStr Detrimental role of humoral signalling in cardio-renal cross-talk
title_full_unstemmed Detrimental role of humoral signalling in cardio-renal cross-talk
title_short Detrimental role of humoral signalling in cardio-renal cross-talk
title_sort detrimental role of humoral signalling in cardio-renal cross-talk
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056806/
https://www.ncbi.nlm.nih.gov/pubmed/24451176
http://dx.doi.org/10.1186/cc13704
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