MHC-Matched Induced Pluripotent Stem Cells Can Attenuate Cellular and Humoral Immune Responses but Are Still Susceptible to Innate Immunity in Pigs

Recent studies have revealed negligible immunogenicity of induced pluripotent stem (iPS) cells in syngeneic mice and in autologous monkeys. Therefore, human iPS cells would not elicit immune responses in the autologous setting. However, given that human leukocyte antigen (HLA)-matched allogeneic iPS...

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Detalles Bibliográficos
Autores principales: Mizukami, Yoshihisa, Abe, Tomoyuki, Shibata, Hiroaki, Makimura, Yukitoshi, Fujishiro, Shuh-hei, Yanase, Kimihide, Hishikawa, Shuji, Kobayashi, Eiji, Hanazono, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057111/
https://www.ncbi.nlm.nih.gov/pubmed/24927426
http://dx.doi.org/10.1371/journal.pone.0098319

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