N-Octanoyl Dopamine Treatment of Endothelial Cells Induces the Unfolded Protein Response and Results in Hypometabolism and Tolerance to Hypothermia

AIM: N-acyl dopamines (NADD) are gaining attention in the field of inflammatory and neurological disorders. Due to their hydrophobicity, NADD may have access to the endoplasmic reticulum (ER). We therefore investigated if NADD induce the unfolded protein response (UPR) and if this in turn influences...

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Detalles Bibliográficos
Autores principales: Stamellou, Eleni, Fontana, Johann, Wedel, Johannes, Ntasis, Emmanouil, Sticht, Carsten, Becker, Anja, Pallavi, Prama, Wolf, Kerstin, Krämer, Bernhard K., Hafner, Mathias, van Son, Willem J., Yard, Benito A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057113/
https://www.ncbi.nlm.nih.gov/pubmed/24926788
http://dx.doi.org/10.1371/journal.pone.0099298

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