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A General Pairwise Interaction Model Provides an Accurate Description of In Vivo Transcription Factor Binding Sites
The identification of transcription factor binding sites (TFBSs) on genomic DNA is of crucial importance for understanding and predicting regulatory elements in gene networks. TFBS motifs are commonly described by Position Weight Matrices (PWMs), in which each DNA base pair contributes independently...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057186/ https://www.ncbi.nlm.nih.gov/pubmed/24926895 http://dx.doi.org/10.1371/journal.pone.0099015 |