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A General Pairwise Interaction Model Provides an Accurate Description of In Vivo Transcription Factor Binding Sites

The identification of transcription factor binding sites (TFBSs) on genomic DNA is of crucial importance for understanding and predicting regulatory elements in gene networks. TFBS motifs are commonly described by Position Weight Matrices (PWMs), in which each DNA base pair contributes independently...

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Detalles Bibliográficos
Autores principales: Santolini, Marc, Mora, Thierry, Hakim, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057186/
https://www.ncbi.nlm.nih.gov/pubmed/24926895
http://dx.doi.org/10.1371/journal.pone.0099015

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