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Lung ventilation strategies and regional lung inflammation
Protective mechanical ventilation is currently accepted as a key strategy for the management of acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome. The study by de Prost and colleagues in the current issue of Critical Care provides new insights into the impact of v...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057236/ https://www.ncbi.nlm.nih.gov/pubmed/24007679 http://dx.doi.org/10.1186/cc12881 |
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author | Luan, Liming Hernandez, Antonio Sherwood, Edward R |
author_facet | Luan, Liming Hernandez, Antonio Sherwood, Edward R |
author_sort | Luan, Liming |
collection | PubMed |
description | Protective mechanical ventilation is currently accepted as a key strategy for the management of acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome. The study by de Prost and colleagues in the current issue of Critical Care provides new insights into the impact of ventilation strategies on pulmonary function, gas exchange, and regional cellular metabolic activity during early ALI in sheep. The group reports that a protective ventilation strategy may attenuate neutrophil activation in dependent lung regions during early experimental ALI. This is an innovative report that provides the basis for further study. |
format | Online Article Text |
id | pubmed-4057236 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40572362014-09-05 Lung ventilation strategies and regional lung inflammation Luan, Liming Hernandez, Antonio Sherwood, Edward R Crit Care Commentary Protective mechanical ventilation is currently accepted as a key strategy for the management of acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome. The study by de Prost and colleagues in the current issue of Critical Care provides new insights into the impact of ventilation strategies on pulmonary function, gas exchange, and regional cellular metabolic activity during early ALI in sheep. The group reports that a protective ventilation strategy may attenuate neutrophil activation in dependent lung regions during early experimental ALI. This is an innovative report that provides the basis for further study. BioMed Central 2013 2013-09-05 /pmc/articles/PMC4057236/ /pubmed/24007679 http://dx.doi.org/10.1186/cc12881 Text en Copyright © 2013 BioMed Central Ltd. |
spellingShingle | Commentary Luan, Liming Hernandez, Antonio Sherwood, Edward R Lung ventilation strategies and regional lung inflammation |
title | Lung ventilation strategies and regional lung inflammation |
title_full | Lung ventilation strategies and regional lung inflammation |
title_fullStr | Lung ventilation strategies and regional lung inflammation |
title_full_unstemmed | Lung ventilation strategies and regional lung inflammation |
title_short | Lung ventilation strategies and regional lung inflammation |
title_sort | lung ventilation strategies and regional lung inflammation |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057236/ https://www.ncbi.nlm.nih.gov/pubmed/24007679 http://dx.doi.org/10.1186/cc12881 |
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