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Analysis for stress environment in the alveolar sac model

Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on...

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Detalles Bibliográficos
Autores principales: Pidaparti, Ramana M., Burnette, Matthew, Heise, Rebecca L., Reynolds, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057278/
https://www.ncbi.nlm.nih.gov/pubmed/24932320
http://dx.doi.org/10.4236/jbise.2013.69110
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author Pidaparti, Ramana M.
Burnette, Matthew
Heise, Rebecca L.
Reynolds, Angela
author_facet Pidaparti, Ramana M.
Burnette, Matthew
Heise, Rebecca L.
Reynolds, Angela
author_sort Pidaparti, Ramana M.
collection PubMed
description Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on actual geometry and the other an idealized spherical geometry using coupled fluid-solid computational analysis. Both the models were analyzed through coupled fluid-solid analysis to estimate the parameters such as pressures/velocities and displacements/stresses under mechanical ventilation conditions. The results obtained from the fluid analysis indicate that both the alveolar geometries give similar results for pressures and velocities. However, the results obtained from coupled fluid-solid analysis indicate that the actual alveolar geometry results in smaller displacements in comparison to a spherical alveolar model. This trend is also true for stress/strain between the two models. The results presented indicate that alveolar geometry greatly affects the pressure/velocities as well as displacements and stresses/strains.
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spelling pubmed-40572782014-06-13 Analysis for stress environment in the alveolar sac model Pidaparti, Ramana M. Burnette, Matthew Heise, Rebecca L. Reynolds, Angela J Biomed Sci Eng Article Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on actual geometry and the other an idealized spherical geometry using coupled fluid-solid computational analysis. Both the models were analyzed through coupled fluid-solid analysis to estimate the parameters such as pressures/velocities and displacements/stresses under mechanical ventilation conditions. The results obtained from the fluid analysis indicate that both the alveolar geometries give similar results for pressures and velocities. However, the results obtained from coupled fluid-solid analysis indicate that the actual alveolar geometry results in smaller displacements in comparison to a spherical alveolar model. This trend is also true for stress/strain between the two models. The results presented indicate that alveolar geometry greatly affects the pressure/velocities as well as displacements and stresses/strains. 2013-09 /pmc/articles/PMC4057278/ /pubmed/24932320 http://dx.doi.org/10.4236/jbise.2013.69110 Text en Copyright © 2013 Ramana M. Pidaparti et al. http://creativecommons.org/licenses/by/2.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Pidaparti, Ramana M.
Burnette, Matthew
Heise, Rebecca L.
Reynolds, Angela
Analysis for stress environment in the alveolar sac model
title Analysis for stress environment in the alveolar sac model
title_full Analysis for stress environment in the alveolar sac model
title_fullStr Analysis for stress environment in the alveolar sac model
title_full_unstemmed Analysis for stress environment in the alveolar sac model
title_short Analysis for stress environment in the alveolar sac model
title_sort analysis for stress environment in the alveolar sac model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057278/
https://www.ncbi.nlm.nih.gov/pubmed/24932320
http://dx.doi.org/10.4236/jbise.2013.69110
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