Cargando…
Analysis for stress environment in the alveolar sac model
Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057278/ https://www.ncbi.nlm.nih.gov/pubmed/24932320 http://dx.doi.org/10.4236/jbise.2013.69110 |
_version_ | 1782320935494221824 |
---|---|
author | Pidaparti, Ramana M. Burnette, Matthew Heise, Rebecca L. Reynolds, Angela |
author_facet | Pidaparti, Ramana M. Burnette, Matthew Heise, Rebecca L. Reynolds, Angela |
author_sort | Pidaparti, Ramana M. |
collection | PubMed |
description | Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on actual geometry and the other an idealized spherical geometry using coupled fluid-solid computational analysis. Both the models were analyzed through coupled fluid-solid analysis to estimate the parameters such as pressures/velocities and displacements/stresses under mechanical ventilation conditions. The results obtained from the fluid analysis indicate that both the alveolar geometries give similar results for pressures and velocities. However, the results obtained from coupled fluid-solid analysis indicate that the actual alveolar geometry results in smaller displacements in comparison to a spherical alveolar model. This trend is also true for stress/strain between the two models. The results presented indicate that alveolar geometry greatly affects the pressure/velocities as well as displacements and stresses/strains. |
format | Online Article Text |
id | pubmed-4057278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
record_format | MEDLINE/PubMed |
spelling | pubmed-40572782014-06-13 Analysis for stress environment in the alveolar sac model Pidaparti, Ramana M. Burnette, Matthew Heise, Rebecca L. Reynolds, Angela J Biomed Sci Eng Article Better understanding of alveolar mechanics is very important in order to avoid lung injuries for patients undergoing mechanical ventilation for treatment of respiratory problems. The objective of this study was to investigate the alveolar mechanics for two different alveolar sac models, one based on actual geometry and the other an idealized spherical geometry using coupled fluid-solid computational analysis. Both the models were analyzed through coupled fluid-solid analysis to estimate the parameters such as pressures/velocities and displacements/stresses under mechanical ventilation conditions. The results obtained from the fluid analysis indicate that both the alveolar geometries give similar results for pressures and velocities. However, the results obtained from coupled fluid-solid analysis indicate that the actual alveolar geometry results in smaller displacements in comparison to a spherical alveolar model. This trend is also true for stress/strain between the two models. The results presented indicate that alveolar geometry greatly affects the pressure/velocities as well as displacements and stresses/strains. 2013-09 /pmc/articles/PMC4057278/ /pubmed/24932320 http://dx.doi.org/10.4236/jbise.2013.69110 Text en Copyright © 2013 Ramana M. Pidaparti et al. http://creativecommons.org/licenses/by/2.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Pidaparti, Ramana M. Burnette, Matthew Heise, Rebecca L. Reynolds, Angela Analysis for stress environment in the alveolar sac model |
title | Analysis for stress environment in the alveolar sac model |
title_full | Analysis for stress environment in the alveolar sac model |
title_fullStr | Analysis for stress environment in the alveolar sac model |
title_full_unstemmed | Analysis for stress environment in the alveolar sac model |
title_short | Analysis for stress environment in the alveolar sac model |
title_sort | analysis for stress environment in the alveolar sac model |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057278/ https://www.ncbi.nlm.nih.gov/pubmed/24932320 http://dx.doi.org/10.4236/jbise.2013.69110 |
work_keys_str_mv | AT pidapartiramanam analysisforstressenvironmentinthealveolarsacmodel AT burnettematthew analysisforstressenvironmentinthealveolarsacmodel AT heiserebeccal analysisforstressenvironmentinthealveolarsacmodel AT reynoldsangela analysisforstressenvironmentinthealveolarsacmodel |