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Homologue engagement controls meiotic DNA break number and distribution
Meiotic recombination promotes genetic diversification as well as pairing and segregation of homologous chromosomes, but the double-strand breaks (DSBs) that initiate recombination are dangerous lesions that can cause mutation or meiotic failure. How cells control DSBs to balance between beneficial...
Autores principales: | Thacker, Drew, Mohibullah, Neeman, Zhu, Xuan, Keeney, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057310/ https://www.ncbi.nlm.nih.gov/pubmed/24717437 http://dx.doi.org/10.1038/nature13120 |
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