Sequential optimization of methotrexate encapsulation in micellar nano-networks of polyethyleneimine ionomer containing redox-sensitive cross-links

A functional polycation nanonetwork was developed for delivery of water soluble chemotherapeutic agents. The complexes of polyethyleneimine grafted methoxy polyethylene glycol (PEI-g-mPEG) and Zn(2+) were utilized as the micellar template for cross-linking with dithiodipropionic acid, followed by an...

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Detalles Bibliográficos
Autores principales: Abolmaali, Samira Sadat, Tamaddon, Ali, Yousefi, Gholamhossein, Javidnia, Katayoun, Dinarvand, Rasoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057327/
https://www.ncbi.nlm.nih.gov/pubmed/24944513
http://dx.doi.org/10.2147/IJN.S61614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057327/
https://www.ncbi.nlm.nih.gov/pubmed/24944513
http://dx.doi.org/10.2147/IJN.S61614

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