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Sequential optimization of methotrexate encapsulation in micellar nano-networks of polyethyleneimine ionomer containing redox-sensitive cross-links
A functional polycation nanonetwork was developed for delivery of water soluble chemotherapeutic agents. The complexes of polyethyleneimine grafted methoxy polyethylene glycol (PEI-g-mPEG) and Zn(2+) were utilized as the micellar template for cross-linking with dithiodipropionic acid, followed by an...
Autores principales: | Abolmaali, Samira Sadat, Tamaddon, Ali, Yousefi, Gholamhossein, Javidnia, Katayoun, Dinarvand, Rasoul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057327/ https://www.ncbi.nlm.nih.gov/pubmed/24944513 http://dx.doi.org/10.2147/IJN.S61614 |
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